See If I Qualify

Life's too short to be struggling with depression that has never responded to treatment.

We help residents in the Gilbert area find real relief from treatment-resistant depression — through a therapeutic approach that works differently than antidepressants, and that often begins delivering results in hours, not weeks.

Clinical research shows 80.4% of patients achieved response or remission with this FDA-approved intranasal treatment.

Recognized by Leaders in Mental Health & Medicine

Our approach is guided by research and protocols developed by respected institutions, including:

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Core Self Brings FDA-Approved Intranasal Treatment to Gilbert

Board-Certified Psychiatric Nurse Practitioners and Licensed Therapists

A Warm, Private Clinical Setting Designed Around Whole-Person Care

REMS-Certified, FDA-Approved Protocols, Medically Supervised

Integrated With Your Existing Psychiatric Care Plan

Free Consultation to Match You With the Right Provider

Fortunately, There Is a Much Better Way to Live.

Traditional antidepressants work for many people — but for those with treatment-resistant depression, they often leave patients feeling stuck, frustrated, and out of options. Side effects, diminishing returns, and months of waiting for relief that never fully arrives can make the path forward feel impossible.

This FDA-approved intranasal treatment is administered under direct medical supervision in our warm, private clinical setting at Core Self. It works through a mechanism distinct from standard antidepressants, and for many patients, it begins restoring relief within hours. It is delivered as part of an integrated, whole-person approach — one that addresses not just your symptoms, but everything that shapes your mental health.

Before Treatment:

  • Persistent Sadness: Living with depression that has not responded to the medications you have already tried

  • Hopelessness: Wondering whether real relief is even possible after a long and exhausting treatment history

  • Social Withdrawal: Pulling away from the people and parts of life that once mattered most to you

  • Cognitive Fog: Struggling to concentrate, make decisions, or get through the ordinary demands of daily life

  • Feeling Stuck: The weight of cycling through treatments without the lasting relief you were promised

After Treatment:

  • Meaningful Relief: Significant improvement in depressive symptoms, often beginning within hours of treatment

  • Renewed Connection: Finding your way back to the relationships and moments that matter most

  • Clearer Thinking: Greater mental clarity and energy for the life you want to be living

  • Restored Hope: A renewed sense of possibility after a long and frustrating journey

  • Whole-Person Care: A treatment plan that looks at all of you — not just a diagnosis

Real Patients. Real Results.

This FDA-approved intranasal treatment delivers rapid, clinically proven relief from treatment-resistant depression — and at Core Self, it is delivered within a whole-person care model designed around you.

Sarah is incredible for medication management! When I first came here, her assessment was so through, and after a few months of working with her, I’m feeling better than I have in years. I also really love seeing Greg & Isaac. They are both so kind and efficient. I can’t recommend this place enough ❤️

- Hailey H.

I am so thankful I found Michaela! I had been to therapy one other time before finding her and I see why you want to find someone who is the right fit because it makes a world of a difference when you find someone who just gets it. She has guided me through incredibly difficult experiences ranging all across the board and brings a sense of calm and empathy to every session. I’m so lucky to have her and don’t know what I would do without her now! I leave our sessions feeling more level-headed and ready to navigate the complexities of life.

- Madison H.

Clinical research shows 80.4% of patients achieved response or remission with this FDA-approved intranasal treatment.

Transformative Experiences in Gilbert

What Patients Who Finally Found Relief With This Intranasal Treatment Have to Say

Explore the journeys of Gilbert residents who found real relief from treatment-resistant depression when nothing else had worked. From rediscovering daily life to reconnecting with the people they love, these are the stories of patients who found a whole-person path forward — and the compassionate team at Core Self that helped them get there.

Clinical research shows 80.4% of patients achieved response or remission with this FDA-approved intranasal treatment.

Have Questions?

What can I expect from the treatment timeline?

Treatment begins with an induction phase of one to two sessions per week during the first several weeks. As your progress is assessed, your provider will adjust your schedule to a maintenance phase tailored to your individual response and goals. Your plan is reviewed throughout treatment to ensure it continues to support your recovery.

What happens during a session?

Each session takes place in our clinical setting at Core Self under direct medical supervision. You will self-administer the nasal spray under provider guidance and then remain in our care for a monitoring period of approximately two hours. You will need a trusted person to drive you home, as you will not be able to drive yourself after treatment.

Is this treatment covered by insurance?

This FDA-approved treatment is covered by many major insurance plans, including Medicare. Coverage and prior authorization requirements vary by plan. Our team will help verify your benefits before your first appointment so you have a clear picture of what to expect before you commit to anything.

How do I know if this treatment is right for me?

This treatment is designed for adults with treatment-resistant depression — those who have tried two or more antidepressants without adequate relief. Our clinical team at Core Self will conduct a thorough evaluation of your history and current condition to determine whether this is the right path forward for you.

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